The formation of Streptococcus mutans persisters induced by the quorum - 2 sensing peptide pheromone is affected by the LexA regulator
نویسندگان
چکیده
sensing peptide pheromone is affected by the LexA regulator 3 4 Vincent Leung, a Dragana Ajdic, b Stephanie Koyanagi, a Céline M. Lévesque a * 5 6 Dental Research Institute, Faculty of Dentistry, University of Toronto, Toronto, Ontario, 7 Canada a , Department of Dermatology and Cutaneous Surgery, University of Miami Miller 8 School of Medicine, Miami, Florida, USA b 9 10 *Corresponding author. Dental Research Institute, Faculty of Dentistry, University of Toronto, 11 124 Edward St., Room 454, Toronto, Ontario M5G 1G6, Canada. Phone: (416) 979-4917, ext. 12 4313. Fax: (416) 979-4936. 13 E-mail: [email protected]. 14
منابع مشابه
The formation of Streptococcus mutans persisters induced by the quorum-sensing peptide pheromone is affected by the LexA regulator.
The presence of multidrug-tolerant persister cells within microbial populations has been implicated in the resiliency of bacterial survival against antibiotic treatments and is a major contributing factor in chronic infections. The mechanisms by which these phenotypic variants are formed have been linked to stress response pathways in various bacterial species, but many of these mechanisms rema...
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Quorum sensing activation by signal pheromone (CSP) in Streptococcus mutans depends on the membrane-associated receptor ComD, which senses the signal and triggers the signaling cascade for bacteriocin production and other cell density-dependent activities. However, the mechanism of the signal recognition via the ComD receptor in this species is nearly unexplored. Here, we show that the membrane...
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